Therapeutics

Providing clinically relevant therapeutics and diagnostics, leveraging our decades of combined clinical experience. Members of BCVT bring a patient-focused approach to developing new therapeutic and diagnostic aids. Pairing state of the art pharmaceutics with new approaches in big data and machine learning, BCVT members have developed online calculators and created novel therapeutic approaches.

Some of our members published work in this area includes:

  1. Stone TJ, DeWitt M, Johnson JW, Beardsley JR, Munawar I, Palavecino E, et al. Analysis of infections among patients with historical culture positive for extended-spectrum beta-lactamase (ESBL)–producing Escherichia coli or Klebsiella pneumoniae: Is ESBL-targeted therapy always needed? Antimicrobial Stewardship & Healthcare Epidemiology [Internet]. 2023 ed [cited 2023 Mar 8];3(1):e47. Available from: https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology/article/analysis-of-infections-among-patients-with-historical-culture-positive-for-extendedspectrum-betalactamase-esblproducing-escherichia-coli-or-klebsiella-pneumoniae-is-esbltargeted-therapy-always-needed/D7BE9834CAACC791958E6FD27B87289A

  2. McNeil CJ, Williamson JC, Muzny CA. Successful Treatment of Persistent 5-Nitroimidazole-Resistant Trichomoniasis With an Extended Course of Oral Secnidazole Plus Intravaginal Boric Acid. Sex Transm Dis. 2023 Apr 1;50(4):243–6.

  3. Williamson JC, Pegram PS. Neuraminidase inhibitors in patients with underlying airways disease. Am J Respir Med. 2002;1(2):85–90.

  4. Chittick P, Williamson JC, Ohl CA. BK virus encephalitis: case report, review of the literature, and description of a novel treatment modality. Ann Pharmacother. 2013 Sep;47(9):1229–33.

  5. Herring AR, Williamson JC. Principles of antimicrobial use in older adults. Clin Geriatr Med. 2007 Aug;23(3):481–97, v.

  6. Logan A, Wolfe A, Williamson JC. Antifungal Resistance and the Role of New Therapeutic Agents. Curr Infect Dis Rep. 2022;24(9):105–16.

  7. Trotman RL, Williamson JC, Shoemaker DM, Salzer WL. Antibiotic dosing in critically ill adult patients receiving continuous renal replacement therapy. Clin Infect Dis. 2005 Oct 15;41(8):1159–66.